At MSU
Preprints and submitted:
25. Jacobson, R.E., Smith, E.W., Saitoh, Y., Qiu, T.A. “Splitting Hairs”: Optimized Sample Preparation Strategy for Mass Spectrometry Imaging of Nematode Caenorhabditis elegans. 2025. Preprint on bioRxiv: doi.org/10.1101/2025.12.01.691628.
24. Reynolds, A.J., Mickel, J.A., Nault, R., Qiu, T.A. (2025) Isomer-specific distribution of perfluorooctane sulfonate (PFOS) in hepatic zonation in mouse. Preprint on bioRxiv: https://www.biorxiv.org/content/10.1101/2025.10.13.682167v1
23. Haffner, J. J., Ahn, S. H., Qiu, T. A. (2025). Revealing Spatial Heterogeneity across the Gut Tissue-Lumen Interface through MALDI Mass Spectrometry Imaging. Preprint on bioRxiv: https://www.biorxiv.org/content/10.1101/2025.06.01.657309v1.
22. Saitoh, Y., Qiu, T. A. (2025). Dynamics of biofilm-forming Bacillus subtilis in Caenorhabditis elegans gut. Preprint on bioRxiv: https://www.biorxiv.org/content/10.1101/2025.01.26.634914v1
Peer-reviewed Publication:
(Underlined & bold: corresponding author from independent career; Underlined: Qiu lab member)
21. Manchanda, R., Aminoroaya, A., Volmert, B., Haffner, J. J., Vaughan, P., Grady, C., Qiu, T. A., Smith, B. R. (2025) Hydrogel-based drug delivery system to treat chemotherapy-induced alopecia. Biomaterials Advances, 178, 214452.
20. Qiu, T. A. Mass spectrometry imaging for spatial toxicology research. Journal of Mass Spectrometry, 2024, 59 (12), e5104. https://doi.org/10.1002/jms.5104
19. Reynolds, A. J., Smith, A., Qiu, T. A. Detection, quantification, and isomer differentiation of per- and polyfluoroalkyl substances (PFAS) using MALDI-TOF with trapped ion mobility. Journal of the American Society for Mass Spectrometry, 2024, 35, 2, 317–325. https://doi.org/10.1021/jasms.3c00369
18. Lee, C. J., Lee, D., Wei, I.-A., Qiu, T. A., Rubakhin, S., Roper, M.G., Sweedler, J. V., Relations between glucose and d-amino acids in the modulation of biochemical and functional properties of rodent islets of Langerhans. ACS Omega, 2023, 8 (50), 47723–47734.
17. Qiu, T. A., Lee, C. J., Huang, C., Rubakhin, S., Lee, D., Romanova, E., Sweedler, J. V., Biodistribution and transformation of gut-absorbed L/D-alanine in germ-free mice. Communications Biology, 2023, 6 (1), 851.
Prior to MSU
Preprints and submitted:
16. Qiu, T. A., Andersen, H. M., Larson, N. J., Schroeder, N. E., Sweedler, J. V. (2021). Identifying sources of d-serine in Caenorhabditis elegans and their impact on behavior. Preprint on ChemRxiv: doi.org/10.33774/chemrxiv-2021-mz0tt
Peer-reviewed Publication:
15. Lee, C. J.*, Qiu, T. A.*, Hong, Z.*, Zhang, Z., Min, Y., Zhang, L., Dai, L., Zhao, H., Si, T., Sweedler, J. V., (2022). Profiling of d-alanine production by the microbial isolates of rat gut microbiota. (*Co-first authors) The FASEB Journal, 36:e22446.
14. Qiu, T. A., Guidolin, V., Hoang, K. N., Pho, T., Carrà, A., Pho, T., Villalta, P. W., He, J., Yao, X., Hamers, R. J., Balbo, S., Feng, Z. V., Haynes, C. L., (2020). Nanoscale battery cathode materials induce DNA damage in bacteria. Chemical Science, 11, 11244-11258.
13. Lee, C. J.*, Qiu, T. A.*, Sweedler, J. V. (2020). d-Alanine: distribution, origin, physiological relevance, and implications in diseases, Biochimica et Biophysica Acta (BBA) – Proteins and Proteomics, 1868(11), 140482. (*Co-first authors)
12. Clement, P. L., Kuether, J. E., Borgatta, J. R., Buchman, J. T., Cahill, M. S., Qiu, T. A., Hamers, R. J., Feng, Z. V., Christy L. H. (2019). Cobalt release from a nanoscale multiphase lithiated cobalt phosphate dominates interaction with Shewanella oneidensis MR-1 and Bacillus subtilis SB491, Chemical Research in Toxicology, 33(3), 806-816.
11. Qiu, T. A., Clement, P. L., Haynes, C. L. (2018). Linking nanomaterial properties to biological outcomes: analytical chemistry challenges in nanotoxicology for the next decade (Invited Perspectives), Chemical Communications, 54, 12787-12803.
10. Olenick, L. L., Troiano, J. M., Vartanian, A. M., Melby, E. S., Zhang, L., Qiu, T. A., Lohse, S. E., Zhang, Xi., Kuech, T. R., Gunsolus, I. L., McGeachy, A., Doğangün, M, Hu, D., Walter, S. R., Lovern, S., Owen, H., Hang, M. N., Torelli, M. D., Feng, Z. V., Hurley, K. R., Dalluge, J., Haynes, C. L., Hamers, R. J., Pedersen, J. A., Cui, Q., Orr, G., Murphy, C. J., Geiger, F. M. (2018). Lipid corona formation from nanoparticle interactions with membranes, Chem, 4(11), 2709-2723.
9. Gallagher, M. J., Buchman, J. T., Qiu, T. A., Zhi, B., Lyons, T. Y., Rosenzweig, Z., Haynes, C. L., Fairbrother, D. H. (2018). Release, detection and toxicity of fragments generated during artificial accelerated weathering of CdSe/ZnS and CdSe quantum dot polymer composites. Environmental Science: Nano, 4(2), 276-281.
8. Zheng, Z., Saar, J., Zhi, B., Qiu, T. A., Gallagher, M. J., Fairbrother, D. H., Haynes, C. L., Lienkamp, K., Rosenzweig, Z. (2018). Structure-property relationships of amine-rich and membrane-disruptive poly(oxonorbornene)-coated gold nanoparticles. Langmuir, 34(15), 4614-4625.
7. Zhi, B., Gallagher, M. J., Frank, B. P., Lyons, T. Y., Qiu, T. A., Da, J., Mensch, A. C., Hamers, R. J., Rosenzweig, Z., Fairbrother, D. H.; Haynes, C. L. (2017). Synthesis and bacterial toxicity of nitrogen and phosphorus co-doped amorphous carbon dots. Carbon, 129, 438-449.
6. Qiu, T. A., Nguyen, T. H. T., Hudson-Smith, N. V., Clement, P. L., Forester, D-C., Frew, H., Hang, M. N., Murphy, C. J., Hamers, R. J., Feng, Z. V., Haynes, C. L. (2017). Growth-based bacterial viability assay for interference-free and high-throughput toxicity screening of nanomaterials. Analytical Chemistry, 89, 2057–2064.
5. Qiu, T. A., Torelli, M. D., Vartanian, A. M., Rackstraw, N. B., Buchman, J. T., Jacob, L. M., Murphy, C. J., Hamers, R. J., Haynes, C. L. (2017). Quantification of free polyelectrolytes present in colloidal suspension, revealing source of toxic responses for polyelectrolyte-wrapped gold nanoparticles. Analytical Chemistry, 89, 1823–1830.
4. Qiu, T. A., Meyer, B. M., Christenson, K. G., Klaper, R. D., Haynes, C. L. (2017). A mechanistic study of TiO2 nanoparticle toxicity on Shewanella oneidensis MR-1 with UV-containing simulated solar irradiation: Bacterial growth, riboflavin secretion, and gene expression. Chemosphere, 168, 1158-1168.
3. Finkenstaedt-Quinn, S. A., Qiu, T. A., Shin K., Haynes, C. L. (2016). Super-resolution imaging for monitoring cytoskeleton dynamics. Analyst, 141, 5674-5688.
2. Qiu, T. A.*, Bozich, J. S.*, Lohse,S. E., Vartanian, A. M., Jacob, L. M., Meyer, B. M., Gunsolus, I. L., Niemuth, N. J., Murphy, C. J., Haynes, C. L., Klaper, R. D. (2015). Gene expression as an indicator of the molecular response and toxicity in the bacterium Shewanella oneidensis and the water flea Daphnia magna exposed to functionalized gold nanoparticles. Environmental Science: Nano, 2, 615-629. (*Co-first authors.)
1. Feng, Z. V., Gunsolus, I. L., Qiu, T. A., Hurley, K., Nyberg, L. H., Frew, H., Johnson, K. P., Vartanian, A. M., Jacob, L. M., Lohse, S. E., Torelli, M. D., Hamers, R. J., Murphy, C. J., Haynes, C. L. (2015). Impacts of gold nanoparticle charge and ligand type on surface binding and toxicity to Gram-negative and Gram-positive bacteria. Chemical Science, 6, 5186-5196.
Invited Research Highlights (Not Peer-reviewed):
3. Allen, C., Qiu, T. A., Pramanik, S., Buchman, J. T., Krause, M. O. P., Murphy, C. J. (2017) Research highlights: Investigating the role of nanoparticle surface charge in nano-bio interactions. Environmental Science: Nano, 4, 741-746.
2. Gallagher, M. J., Allen, C., Buchman, J. T., Qiu, T. A., Clement, P. L., Krause, M. O. P., Gilbertson, L. M. (2017). Research highlights: applications of life-cycle assessment as a tool for characterizing environmental impacts of engineered nanomaterials. Environmental Science: Nano, 4, 276-281.
1. Qiu, T. A., Gallagher, M. J., Hudson-Smith, N. V., Wu, J., Krause, M. O. P., Fortner, J. D., Haynes, C. L. (2016) Research highlights: unveiling the mechanisms underlying nanoparticle-induced ROS generation and oxidative stress. Environmental Science: Nano, 3, 940-945.
Qiu Research Lab 